All Trans Retinoic Acid Inhibits Collagen Deposition in Extracellular Matrix of Uterine Smooth Muscle Cells

Friday, November 7, 2014
Plaza Foyer (Sheraton)
Sunada Khadka , Wesleyan College
This study incorporates the anti-proliferative effect induced by the treatment of uterine smooth muscle cells with all trans retinoic acid. This provides a basis for understanding the mechanism and treatment options for certain uterine pathologies like leiomyomas, characterised by the over-expression of collagen in extracellular matrix of these cells.