All Trans Retinoic Acid Inhibits Collagen Deposition in Extracellular Matrix of Uterine Smooth Muscle Cells

This study incorporates the anti-proliferative effect induced by the treatment of uterine smooth muscle cells with all trans retinoic acid. This provides a basis for understanding the mechanism and treatment options for certain uterine pathologies like leiomyomas, characterised by the over-expression of collagen in extracellular matrix of these cells.