Investigation of Lysozyme Modifications By 2-Chloro-1,4-Benzoquinone

Lysozyme can be modified by 2-chloro-1,4-benzoquinone (CBQ), a possible metabolite of the family of atmospheric pollutants called polycyclic aromatic hydrocarbons. This modification can lead to several severe effects including amyloidosis, a process by which globular proteins aggregate and become insoluble. This project examines the effects of CBQ on lysozyme.