Investigation of Lysozyme Modifications By 2-Chloro-1,4-Benzoquinone

Friday, November 7, 2014
Plaza Foyer (Sheraton)
Hendrik Greve , University of Tennessee at Chattanooga
Lysozyme can be modified by 2-chloro-1,4-benzoquinone (CBQ), a possible metabolite of the family of atmospheric pollutants called polycyclic aromatic hydrocarbons. This modification can lead to several severe effects including amyloidosis, a process by which globular proteins aggregate and become insoluble. This project examines the effects of CBQ on lysozyme.