Solid phase synthesis of ferrocene-biotin bioconjugates for the development of electrochemical biosensors

As a means of developing ferrocene based biosensors, we have produced a library of ferrocene-biotin bio-conjugates which we have systematically evaluated electrochemically for their change in redox activity in the absence and presence of avidin. These proposed biosensors are to be employed as a compliment to common imaging modalities in the detection of cancer.